Hong Lab

Welcome to the Hong Lab 

Decoding the molecular mechanisms of PAH to develop targeted therapies.

We are a research group at UCLA dedicated to uncovering the molecular mechanisms of pulmonary arterial hypertension (PAH) and related pulmonary vascular diseases. By integrating experimental and multiomics approaches, we aim to identify disease-driving pathways and develop targeted therapies to improve patient outcomes.

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In the News

A doctor in lab coat typing on a computer

UCLA faculty honored by the American Society for Clinical Investigation

February 24, 2025

Four UCLA Health faculty have been elected to the American Society for Clinical Investigation (ASCI) while two others have earned Young Physician-Scientist Awards. All are members of the department of medicine at UCLA Health. 

Read UCLA Health Article
 


 


 

Illustration of human lungs and surrounding blood vessels within the chest.

UCLA-led study unveils new insights and potential treatments for pulmonary hypertension

August 21, 2024

A new study from researchers with UCLA Health and collaborating organizations has found that asporin, a protein encoded by the ASPN gene, plays a protective role in pulmonary arterial hypertension (PAH).

Read UCLA Health Article
 


 

Clinician reviewing chest X-ray images on a lightbox.

Q&A: Asporin linked to ‘more favorable disease profile’ in patients with PAH

October 02, 2024

In PAH lung samples, researchers observed elevated asporin levels and found a link between these levels and lower disease severity.

Read Healio Article


 

Researcher using a microscope in a laboratory.

New insights and potential treatments for pulmonary hypertension

August 21, 2024

A new study has found that asporin, a protein encoded by the ASPN gene, plays a protective role in pulmonary arterial hypertension (PAH).

Read Science Daily Article