Publications

  1. A Cross-Species and Sex-Specific Meta-Analysis of Transcriptomic Studies of Pulmonary Hypertension. Zhao L, Cunningham CM, Hong J, Agarwal S, Yuan K, de Jesus Perez VA, Nicolls MR. Am J Respir Cell Mol Biol, 2025. PMID: 39928415.
  2. Dissecting the Lung Transcriptome of Pulmonary Fibrosis-associated Pulmonary Hypertension. Brownstein AJ, Mura M, Ruffenach G, Channick RN, Saggar R, Kim A, Umar S, Eghbali M, Yang X, Hong J†. Am J Physiol Lung Cell Mol Physiol, 2024. PMID: 39137526.
  3. Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension. Hong J*, Medzikovic L*, Sun W, Wong B, Ruffenach G, Rhodes CJ, Brownstein A, Liang LL, Aryan L, Li M, Vadgama A, Kurt Z, Schwantes-An T, Mickler EA, Gräf S, Eyries M, Lutz KA, Pauciulo MW, Trembath RC, Perros F, Montani D, Morrell NW, Soubrier F, Wilkins MR, Nichols WC, Aldred MA, Desai AA, Trégouët DA, Umar S, Saggar R, Channick R, Tuder RM, Geraci MW, Stearman RS, Yang X, Eghbali M. Circulation, 2024. PMID: 39167456.
  4. Digital Spatial Profiling Identifies Distinct Molecular Signatures of Vascular Lesions in Pulmonary Arterial Hypertension. Tuder RM, Gandjeva A, Williams S, Kumar S, Kheyfets VO, Hatton-Jones KM, Starr JR, Yun J, Hong J, West NP, Stenmark KR. Am J Respir Crit Care Med, 2024. PMID: 38568479.
  5. Charting the Cellular Landscape of Pulmonary Arterial Hypertension Through Single-Cell Omics. Tang B, Vadgama A, Redmann B, Hong J†. Respir Res, 2024. PMID: 38702687.
  6. Function of RNA Binding Protein in Cardiovascular Disease. Ruffenach G, Medzikovic L, Sun W, Hong J, Eghbali M. Cells, 2023. PMID: 38132114.
  7. Thoracic Spinal Cord Neuroinflammation as a Novel Therapeutic Target in Pulmonary Hypertension. Razee A, Banerjee S, Hong J, Magaki S, Fishbein G, Ajijola OA, Umar S. Hypertension, 2023. PMID: 37092338.
  8. Myocardial fibrosis and calcification are attenuated by microRNA-129-5p targeting Asporin and Sox9 in cardiac fibroblasts. Medzikovic L, Aryan L, Ruffenach G, Li M, Savalli N, Sun W, Sarji S, Hong J, Sharma S, Olcese R, Fishbein G, Eghbali M. JCI Insight, 2023. PMID: 37154157.
  9. Tm4sf1-marked Endothelial Subpopulation Is Dysregulated in Pulmonary Arterial Hypertension. Hong J‡, Wong B, Huynh C, Tang B, Ruffenach G, Li M, Umar S, Yang X, Eghbali M. Am J Respir Cell Mol Biol, 2023. PMID: 36252184.
  10. Comparative Analysis of Right Ventricular Metabolic Reprogramming in Preclinical Rat Models of Severe Pulmonary Hypertension-induced Right Ventricular Failure. Banerjee S, Hong J, Umar S. Front Cardiovasc Med, 2022. PMID: 36158812.
  11. Y-Chromosome Gene, Uty, Protects Against Pulmonary Hypertension by Reducing Proinflammatory Chemokines. Cunningham CM, Li M, Ruffenach G, Doshi M, Aryan L, Hong J, Park J, Hrncir H, Medzikovic L, Umar S, Arnold AP, Eghbali M. Am J Respir Crit Care Med, 2022. PMID: 35504005.
  12. Significance of Autoimmune Disease in Severe Pulmonary Hypertension Complicating Extensive Pulmonary Fibrosis: A Prospective Cohort Study. Saggar R, Giri PC, Chunqin D, Johnson D, McCloy MK, Lloyd L, Faisal S, Hong J, Channick RN, SS, Lynch III JP, Belperio JA., Weigt SS, Ramsey A, Ross DJ, Sayah D, Shino M, Derhovanessian A, Sherman A, Saggar R. Pulm Circ, 2021. PMID: 33996029.
  13. Transcriptomic Analysis of Right Ventricular Remodeling in Two Rat Models of Pulmonary Hypertension: Identification and Validation of Epithelial-to-Mesenchymal Transition in Human Right Ventricular Failure. Park JF, Clark VR, Banerjee S, Hong J, Razee A, Williams T, Fishbein G, Saddic L, Umar S. Circ Heart Fail, 2021. PMID: 33541093.
  14. Single-cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning. Hong J‡, Arneson D, Umar S, Ruffenach G, Cunningham CM, Ahn IS, Diamante G, Bhetraratana M, Park JF, Said E, Huynh C, Le T, Medzikovic L, Humbert M, Soubrier F, Montani D, Girerd B, Trégouët D-A, Channick R, Saggar R, Eghbali M, Yang X. Am J Respir Crit Care Med, 2021. PMID: 33021809.
  15. Pulmonary hypertension secondary to pulmonary fibrosis: clinical data, histopathology and molecular insights. Ruffenach G, Hong J, Vaillancourt M, Medzikovic L, Eghbali M. Respir Res, 2020. PMID: 33208169.
  16. Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-19. Medzikovic L, Cunningham CM, Li M, Amjedi M, Hong J, Ruffenach G, Eghbali M. J Mol Cell Cardiol, 2020. PMID: 32835666. 
  17. Oral 15-Hydroxyeicosa​tetra​enoic Acid Induces Pulmonary Hypertension in Mice by Triggering T Cell-Dependent Endothelial Cell Apoptosis. Ruffenach G, O’Connor E, Vaillancourt M, Hong J, Cao N, Sarji S, Moazeni S, Papesh J, Grijalva V, Cunningham CM, Shu L, Chattopadhyay A, Tiwari S, Mercier O, Perros F, Umar S, Yang X, Gomes AV, Fogelman AM, Reddy ST, Eghbali M. Hypertension, 2020. PMID: 32713273.
  18. Single-cell RNA-seq analysis of the brainstem of mutant SOD1 mice reveals perturbed cell types and pathways of amyotrophic lateral sclerosis. Liu W, Venugopal S, Majid S, Ahn IS, Diamante G, Hong J, Yang X, Chandler SH. Neurobiol Dis, 2020. PMID: 32360664.
  19. Involvement of Low Density Lipoprotein Receptor in the Pathogenesis of Pulmonary Hypertension. Umar S, Ruffenach G, Moazeni S, Vaillancourt M, Hong J, Cunningham CM, Cao N, Navab S, Sarji S, Lee L, Li M, Fishbein G, Ardehali A, Navab M, Reddy ST, Eghbali M. J Am Heart Assoc, 2020. PMID: 31914876.
  20. Differential Metabolic and Multi-tissue Transcriptomic Responses to Fructose Consumption among Genetically Diverse Mice. Zhang G, Byun HR, Ying Z, Zhao Y, Hong J, Shu L, Gomez-Pinilla F, Yang X. Biochim Biophys Acta Mol Basis Dis, 2020. PMID: 31669422.
  21. Diesel exhaust particles dysregulate multiple immunological pathways in murine macrophages: Lessons from microarray and scRNA-seq technologies. Bhetraratana M, Orozco LD, Hong J, Diamante G, Majid S, Bennett BJ, Ahn IS, Yang X, Lusis AJ, Araujo JA. Arch Biochem Biophys, 2019. PMID: 31568751.
  22. Histological hallmarks and role of Slug/PIP axis in pulmonary hypertension secondary to pulmonary fibrosis. Ruffenach G, Umar S, Vaillancourt M, Cao N, Hong J, Sarji S, Moazeni S, Cunningham C, Ardehali A, Reddy ST, Saggar R, Fishbein G, Eghbali M. EMBO Mol Med, 2019. PMID: 31468711.